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129585

Sigma-Aldrich

Maleimide

99%

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Synonym(s):
2,5-Pyrroledione
Empirical Formula (Hill Notation):
C4H3NO2
CAS Number:
Molecular Weight:
97.07
Beilstein/REAXYS Number:
106910
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

powder

mp

91-93 °C (lit.)

SMILES string

O=C1NC(=O)C=C1

InChI

1S/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)

InChI key

PEEHTFAAVSWFBL-UHFFFAOYSA-N

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1 of 4

This Item
JKA7029JKA7018JKA8027
Maleimide 99%

129585

Maleimide

4arm-PEG20K-Maleimide average Mn 20,000

JKA7029

4arm-PEG20K-Maleimide

4arm-PEG10K-Maleimide average Mn 10,000

JKA7018

4arm-PEG10K-Maleimide

8arm-PEG10K-Maleimide hexaglycerol core, average Mn 10,000

JKA8027

8arm-PEG10K-Maleimide

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

mp

91-93 °C (lit.)

mp

-

mp

-

mp

-

form

powder

form

solid

form

solid

form

solid

General description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Maleimide is used as a dienophile in Diels Alder reaction for the synthesis of macromolecules.

Application

Rhodium-catalyzed conjugate arylation with arylboronic acids.
The maleimide-functionalized silica beads were used to immobilize the bovine serum albumin (BSA)-boronic acid (BA) conjugates.

pictograms

CorrosionSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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We report bovine serum albumin (BSA)-boronic acid (BA) conjugates as lectin mimetics and their glyco-capturing capacity. The BSA-BA conjugates were synthesized by amidation of carboxylic acid groups in BSA with aminophenyl boronic acid in the presence of EDC, and were

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