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130532

Sigma-Aldrich

5,7-Dichloro-8-hydroxy-2-methylquinoline

98%

Synonym(s):

5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM

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About This Item

Empirical Formula (Hill Notation):
C10H7Cl2NO
CAS Number:
72-80-0
Molecular Weight:
228.07
Beilstein/REAXYS Number:
156683
EC Number:
200-789-3
MDL number:
MFCD00023984
UNSPSC Code:
12352100
PubChem Substance ID:
24847966
NACRES:
NA.22

Quality Level

200

assay

98%

mp

108-112 °C (dec.) (lit.)

functional group

chloro

SMILES string

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

InChI key

GPTXWRGISTZRIO-UHFFFAOYSA-N

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Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9893
BCCJ5523
BCCF7602
BCCC6368
BCBX0666

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Tzu-Shean Feng et al.
Biochemical pharmacology, 82(3), 236-247 (2011-05-21)
4-Aminoquinolines were hybridized with artemisinin and 1,4-naphthoquinone derivatives via the Ugi-four-component condensation reaction, and their biological activities investigated. The artemisinin-containing compounds 6a-c and its salt 6c-citrate were the most active target compounds in the antiplasmodial assays. However, despite the potent
Contact cross-sensitization among quinolines.
A Rodríguez et al.
Allergy, 56(8), 795-795 (2001-08-08)
A Neiger et al.
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 79(31-32), 918-920 (1990-08-02)
Besides the various operative procedures, which nowadays have come into use in hemorrhoidal disorders, drug therapy as well continues to keep an important place. Its main conditions of application are inflammatory processes before, between and after hemorrhoidal sclerosis or proctological
Allergic contact dermatitis due to benzoyl peroxide in an arm prosthesis.
C Vincenzi et al.
Contact dermatitis, 24(1), 66-67 (1991-01-01)
Cutaneous drug reaction case reports: from the world literature.
American journal of clinical dermatology, 3(1), 63-69 (2002-01-31)
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