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Sigma-Aldrich

9(10H)-Acridanone

99%

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Synonym(s):
Acridone, 9,10-Dihydro-9-oxoacridine
Empirical Formula (Hill Notation):
C13H9NO
CAS Number:
578-95-0
Molecular Weight:
195.22
Beilstein/REAXYS Number:
7104
EC Number:
209-434-7
MDL number:
MFCD00005019
UNSPSC Code:
12352100
PubChem Substance ID:
24848848
NACRES:
NA.22

Quality Level

100

assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm
399 nm (2nd)

SMILES string

O=C1c2ccccc2Nc3ccccc13

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243)

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Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

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2-METHOXY-9(10H)-ACRIDONE AldrichCPR

S580384

2-METHOXY-9(10H)-ACRIDONE

Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Jacob M Goldberg et al.
Journal of the American Chemical Society, 134(14), 6088-6091 (2012-04-05)
Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of
Jatinder Kaur et al.
Chemical communications (Cambridge, England), 47(15), 4472-4474 (2011-03-08)
Acridones carrying an appropriate substituent at N-10 showed significant fluorescence changes on interacting with ATP in HEPES buffer at pH 7.2. The selectivity and sufficient binding of these probes with ATP could be useful for monitoring of metabolic processes.
Vishal P Zambre et al.
Journal of molecular graphics & modelling, 29(2), 229-239 (2010-08-10)
G-quadruplex structures of DNA represent a potentially useful target for anticancer drugs. Telomerase enzyme, involved in immortalization of cancer cells is inhibited by stabilization of G-quadruplex at the ends of chromosomes. Anthraquinone and acridone derivatives are promising G-quadruplex ligands as
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