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150215

Sigma-Aldrich

9(10H)-Acridanone

99%

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Synonym(s):
Acridone, 9,10-Dihydro-9-oxoacridine
Empirical Formula (Hill Notation):
C13H9NO
CAS Number:
Molecular Weight:
195.22
Beilstein:
7104
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

Assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm
399 nm (2nd)

SMILES string

O=C1c2ccccc2Nc3ccccc13

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243)

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This Item
148318517927775525
9(10H)-Acridanone 99%

Sigma-Aldrich

150215

9(10H)-Acridanone

form

solid

form

-

form

solid

form

solid

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

~289 °C (dec.)

mp

144-149 °C

λmax

380 nm

λmax

-

λmax

-

λmax

-

Gene Information

human ... ABCB1(5243)

Gene Information

-

Gene Information

-

Gene Information

-

Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jatinder Kaur et al.
Chemical communications (Cambridge, England), 47(15), 4472-4474 (2011-03-08)
Acridones carrying an appropriate substituent at N-10 showed significant fluorescence changes on interacting with ATP in HEPES buffer at pH 7.2. The selectivity and sufficient binding of these probes with ATP could be useful for monitoring of metabolic processes.
Vishal P Zambre et al.
Journal of molecular graphics & modelling, 29(2), 229-239 (2010-08-10)
G-quadruplex structures of DNA represent a potentially useful target for anticancer drugs. Telomerase enzyme, involved in immortalization of cancer cells is inhibited by stabilization of G-quadruplex at the ends of chromosomes. Anthraquinone and acridone derivatives are promising G-quadruplex ligands as
Anton V Dubrovskiy et al.
The Journal of organic chemistry, 77(24), 11232-11256 (2012-12-05)
A novel, efficient route to biologically and pharmaceutically important o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles has been developed starting from readily available hydrazones of aldehydes and o-(trimethylsilyl)aryl triflates. The reaction proceeds through arynes under mild conditions, tolerates a wide
Alessandra Di Veroli et al.
Environmental pollution (Barking, Essex : 1987), 166, 212-217 (2012-04-21)
The aim of the present study was to improve the cause-effect relationship between toxicant exposure and chironomid mouthpart deformities, by linking induction of mouthpart deformities to contaminated field sediments, metal mixtures and a mutagenic polycyclic aromatic compound metabolite (acridone). Mouthpart
Jacob M Goldberg et al.
Journal of the American Chemical Society, 134(14), 6088-6091 (2012-04-05)
Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of

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