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159506

Sigma-Aldrich

4-Tritylaniline

97%

Synonym(s):

4-Triphenylmethylaniline

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About This Item

Linear Formula:
(C6H5)3CC6H4NH2
CAS Number:
Molecular Weight:
335.44
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

mp

255-257 °C (lit.)

functional group

phenyl

SMILES string

Nc1ccc(cc1)C(c2ccccc2)(c3ccccc3)c4ccccc4

InChI

1S/C25H21N/c26-24-18-16-23(17-19-24)25(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-19H,26H2

InChI key

XYHDHXBLSLSXSR-UHFFFAOYSA-N

General description

4-Tritylaniline is also referred as p-tritylaniline.

Application

4-Tritylaniline was used in the preparation of:
  • 5-tritylisatin
  • 2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(4-tritylanilinocarbonyl)-9H-xanthene methanol trisolvate monohydrate
  • bis-4,4-[6-chloro-N-(4-tritylphenyl)-[1,3,5]triazine-2,4-diamine]-[2,2-disulfonic acid]-stilbene, novel fluorophore, with potential application as an optical brightener

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis of a Fluorophore with Improved Optical Brightness.
Okuom M, et al.
International Journal of Organic Chemistry (2013)
2, 7-Di-tert-butyl-9, 9-dimethyl-4, 5-bis (4-tritylanilinocarbonyl)-9H-xanthene methanol trisolvate monohydrate.
Vysotsky MO and Schollmeyer D.
Acta Crystallographica Section E, Structure Reports Online, 63(1), o169-o171 (2006)
Larry L Klein et al.
Tetrahedron letters, 54(8), 1008-1011 (2013-03-08)
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an
Salvatore Debonis et al.
Journal of medicinal chemistry, 51(5), 1115-1125 (2008-02-13)
The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis with a characteristic monoastral spindle phenotype. Prolonged metaphase block eventually leads to apoptotic cell death. S-trityl-L-cysteine (STLC) is a

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