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161969

Sigma-Aldrich

Triethylenetetramine tetrahydrochloride

97%

Synonym(s):

Cuprior, Trientine tetrahydrochloride

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About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2 · 4HCl
CAS Number:
Molecular Weight:
292.08
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

mp

269-270 °C (lit.)

SMILES string

Cl.Cl.Cl.Cl.NCCNCCNCCN

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChI key

OKHMDSCYUWAQPT-UHFFFAOYSA-N

General description

Triethylenetetramine tetrahydrochloride is a copper-chelating agent

Application

Triethylenetetramine tetrahydrochloride was used as primary amine displacer in affinity chromatography.

Biochem/physiol Actions

Triethylenetetramine tetrahydrochloride induces apoptosis of acinar cells of the pancreas in male Fischer 344 rats.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Male Fischer 344 rats weighing 80-90 g were fed on a copper-depleted diet supplemented with 0.6% triethylenetetramine tetrahydrochloride (a copper chelator), and the death of pancreatic acinar cells of these rats was investigated morphologically and biochemically. The weight of the
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