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199656

Sigma-Aldrich

Sudan II

Dye content 90 %

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Synonym(s):
1-(2,4-Xylylazo)-2-naphthol, Solvent Orange 7
Empirical Formula (Hill Notation):
C18H16N2O
CAS Number:
3118-97-6
Molecular Weight:
276.33
Colour Index Number:
12140
EC Number:
221-490-4
MDL number:
MFCD00003896
UNSPSC Code:
12171500
PubChem Substance ID:
24851931
NACRES:
NA.47

form

powder

Quality Level

100

composition

Dye content, 90%

mp

156-158 °C (lit.)

solubility

chloroform: 10 mg/mL

λmax

493 nm
604 nm (2nd)

ε (extinction coefficient)

≥14000 at 491-497 nm in methanol at 0.005 g/L
≥9000 at 419-425 nm in methanol at 0.005 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cc1ccc(\N=N\c2c(O)ccc3ccccc23)c(C)c1

InChI

1S/C18H16N2O/c1-12-7-9-16(13(2)11-12)19-20-18-15-6-4-3-5-14(15)8-10-17(18)21/h3-11,21H,1-2H3/b20-19+

InChI key

JBTHDAVBDKKSRW-FMQUCBEESA-N

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Application

Sudan II has been used to determine its presence in commercial spices such as hot chilli food samples (LC–ESI–MS/MS).

Biochem/physiol Actions

Sudan II is a fat-soluble synthetic colorant and it belongs to the group of azo compounds. It is classified by the international agency for research on cancer (IARC) as category 3 carcinogens because it has an ability to cause certain forms of liver and bladder cancer in animals.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Simultaneous determination of water-soluble and fat-soluble synthetic colorants in foodstuff by high-performance liquid chromatography-diode array detection-electrospray mass spectrometry.
Ma M
Journal of Chromatography A, 1103, 170-176 (2006)
Shuo Sun et al.
Journal of separation science, 34(14), 1730-1737 (2011-06-10)
The liquid-liquid microextraction (LLME) was developed for extracting sudan dyes from red wine and fruit juice. Room temperature ionic liquid was used as the extraction solvent. The target analytes were determined by high-performance liquid chromatography. The extraction parameters were optimized.
Shane T Finn et al.
Photochemistry and photobiology, 87(5), 1184-1188 (2011-06-15)
We describe a screening methodology that can be used to quickly determine the effectiveness of newly synthesized photocatalysts. We were particularly interested in measuring the destruction of organic molecules painted onto a photocatalytic surface by spraying, with destruction proceeding in
Ting Xu et al.
Analytical biochemistry, 405(1), 41-49 (2010-06-05)
To obtain antibodies to develop an enzyme-linked immunosorbent assay (ELISA) for the analysis of Sudan red I, haptens were designed and synthesized via four different strategies: (i) attachment of a spacer at the para position of the benzene ring, (ii)
Jing Liu et al.
Analytical biochemistry, 423(2), 246-252 (2012-02-14)
Many methods have been reported to determine the residues of Sudan dyes in food samples. Among the reported methods, enzyme-linked immunosorbent assay (ELISA) was a frequently used practical screen tool. In this study, a novel hapten of Sudan 2 was
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