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260428

Sigma-Aldrich

3-Ethoxy-1,2-propanediol

98%

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Synonym(s):
3-Ethoxypropane-1,2-diol, Glycerol 1-ethyl ether
Linear Formula:
C2H5OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
120.15
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

98%

form

liquid

refractive index

n20/D 1.441 (lit.)

bp

222 °C (lit.)

density

1.063 g/mL at 25 °C (lit.)

SMILES string

CCOCC(O)CO

InChI

1S/C5H12O3/c1-2-8-4-5(7)3-6/h5-7H,2-4H2,1H3

InChI key

LOSWWGJGSSQDKH-UHFFFAOYSA-N

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This Item
251739438960572535
3-Ethoxy-1,2-propanediol 98%

260428

3-Ethoxy-1,2-propanediol

3-Allyloxy-1,2-propanediol 99%

251739

3-Allyloxy-1,2-propanediol

density

1.063 g/mL at 25 °C (lit.)

density

1.068 g/mL at 25 °C (lit.)

density

-

density

-

refractive index

n20/D 1.441 (lit.)

refractive index

n20/D 1.462 (lit.)

refractive index

-

refractive index

-

bp

222 °C (lit.)

bp

142 °C/28 mmHg (lit.)

bp

-

bp

-

form

liquid

form

liquid

form

solid

form

solid

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

General description

3-Ethoxy-1,2-propanediol (also known as glycerol α-ethyl ether) is primarily used as a solvent in various industries, including pharmaceuticals, cosmetics, and coatings. It can also be used as a substrate in the synthesis of cyclic phosphates for use in flame retardants.

Application

3-Ethoxy-1,2-propanediol (EGE) can be used as a crosslinking agent in the development of poly(glycidol) hydrogels for use in various biomedical applications such as tissue engineering and drug delivery. It is also used as a potential component in a bio-based solvent system for dissolving or processing nitrocellulose.

3-Ethoxy-1,2-propanediol can be used as:

  • An analyte protector in gas chromatographic analysis of pesticides.
  • An acceptor substrate in glycosylation reaction by sucrose phosphorylase.
It can also be used as a precursor in the Mitsunobu reaction of N-hydroxy phthalimide with poly(glycidol) and synthesis of 2-(3-ethoxy-2-hydroxypropoxy) isoindoline-1,3-dione.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Steven J Lehotay et al.
Journal of agricultural and food chemistry, 68(5), 1468-1479 (2020-01-17)
In this study, sample processing of bulk commodities using an efficient one-step comminution procedure with liquid nitrogen (LN2) was devised and assessed in the analysis of pesticide residues in fruits and vegetables. LN2 was added to the fresh samples from
Lucia Ivorra et al.
Chemosphere, 235, 662-669 (2019-07-06)
Uptake and depuration kinetics of 4,4'-dichlorobenzophenone (main metabolite of dicofol) in the edible clam Meretrix meretrix were evaluated through a mesocosm experiment. M. meretrix was exposed to different dicofol concentrations (environmental concentration, D1 = 50 ng/L; supra-environmental concentration, D2 = 500 ng/L) for 15 days, followed by
Jian Du et al.
Scientific reports, 6, 38355-38355 (2016-12-08)
The presence of pesticides in human milk (HM) is of great concern due to the potential health effects for the breastfed infant. To determine the relationships between HM pesticides and infant growth and development, a longitudinal study was conducted. HM
Lijun Han et al.
Journal of agricultural and food chemistry, 66(20), 4986-4996 (2017-11-15)
In this study, analytical results were compared when using different approaches to bulk food sample comminution, consisting of a vertical chopper (Blixer) at room temperature and dry ice cryogenic conditions, followed by further subsample processing (20 g) using liquid nitrogen
Jian Du et al.
Chemosphere, 167, 247-254 (2016-10-12)
Persistent organic pollutants in human milk (HM) at high levels are considered to be detrimental to the breastfed infant. To determine the pesticide concentration in HM, a pilot cross-sectional study of 40 Western Australian (WA) women was carried out. Gas

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