290998

Pentylmagnesium bromide solution

2.0 M in diethyl ether

• Synonym(s): 1-Pentylmagnesium bromide, n-Pentylmagnesium bromide, Amylmagnesium bromide, Bromopentylmagnesium
• Linear Formula: C₅H₁₁MgBr
• CAS Number: 693-25-4
• Molecular Weight: 175.35
• MDL number: MFCD00000045
• UNSPSC Code: 12352001
• PubChem Substance ID: 24857502
• NACRES: NA.22

Properties

• Quality Level: 100
• reaction suitability: reaction type: Grignard Reaction
• concentration: 2.0 M in diethyl ether
• density: 0.947 g/mL at 25 °C
• SMILES string: CCCCC[Mg]Br
• InChI: 1S/C5H11.BrH.Mg/c1-3-5-4-2;;/h1,3-5H2,2H3;1H;/q;;+1/p-1
• InChI key: ZXWGTPYWPZGZPT-UHFFFAOYSA-M

Description

Application

Pentylmagnesium bromide solution is a Grignard reagent that can be used in the preparation of:

• Alkanes via Ni or Cu-catalyzed cross-coupling reaction with alkyl fluorides.
• Hydroxypiperidinones via the addition-cyclization-deprotection process of aldimines.

It can also be used as a reagent to synthesize a key intermediate by olefin alkylation in the total synthesis of alkaloid, (+)-hyperaspine , and surface alkylation of H-terminated Si (111), by Si-C bond formation.

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H260,H302,H314,H336
• pcodes: P210 - P231 + P232 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• target_organs: Central nervous system
• supp_hazards: EUH014,EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: -40.0 °F - closed cup
• flash_point_c: -40 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter