298174

Sodium tetrachloroaurate(III) dihydrate

99%

• Synonym(s): Sodium gold chloride
• Linear Formula: NaAuCl₄ · 2H₂O
• CAS Number: 13874-02-7
• Molecular Weight: 397.80
• NACRES: NA.23
• PubChem Substance ID: 24857964
• UNSPSC Code: 12352302
• EC Number: 239-241-3
• MDL number: MFCD00149162
• Assay: 99%
• Form: solid

Properties

• Quality Level: 100
• assay: 99%
• form: solid
• reaction suitability: core: sodium, reagent type: catalyst
• SMILES string: O.O.[Na+].Cl[Au-](Cl)(Cl)Cl
• InChI: 1S/Au.4ClH.Na.2H2O/h;4*1H;;2*1H2/q+3;;;;;+1;;/p-4
• InChI key: OEERDTKOVZFOHF-UHFFFAOYSA-J

Description

General description

Sodium tetrachloroaurate(III) dihydrate (NaAuCl₄·2H₂O) is the least expensive gold catalyst that is widely used in many organic transformations such as nucleophilic addition to multiple bonds, nonsymmetrical etherization, and nucleophilic substitution of propargylic alcohols.

Application

Sodium tetrachloroaurate(III) dihydrate can be used as a catalyst:

• To synthesize 1,5-benzodiazepine and quinoxaline derivatives, which are important heterocycles in pharmaceuticals.
• For efficient deprotection of tert-butyl(dimethyl)silyl (TBS) protecting groups by a simple and mild method.

It can also be used as a precursor in the synthesis of gold nanoparticles.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves