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Key Documents

348104

Sigma-Aldrich

Triphenyltin hydroxide

Synonym(s):

Fentin hydroxide, Hydroxytriphenylstannane, NSC 113243

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About This Item

Linear Formula:
(C6H5)3SnOH
CAS Number:
Molecular Weight:
367.03
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

mp

124-126 °C (lit.)

SMILES string

O[Sn](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1

InChI key

BFWMWWXRWVJXSE-UHFFFAOYSA-M

Application

Reactant involved in transmetalation reactions with Ir clusters

Reactant involved in synthesis of:
  • (E)-(Nitrophenyl)propenoic acid organotin(IV) carboxylates with antitumor activity
  • Triorganotin chrysanthemumates for larvicidal studies
  • Polynuclear organotin(IV) carboxylates containing ferrocenyl moieties for antitumor investigation
  • Organotin(IV) aminophenylacrylate complexes
  • 4-Biphenylcarboxylic acid derivatives for in vitro cytotoxicity studies

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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H Matsui et al.
Experientia, 40(4), 377-378 (1984-04-15)
The sensitivity to the diabetogenic action of triphenyltin hydroxide (TPTOH) was investigated in 5 species of experimental animals. A single oral administration of TPTOH produced marked hyperglycemia and triglyceridemia in rabbits and hamsters, but no evidence of diabetes was found
C O Knowles et al.
Environmental research, 39(1), 172-179 (1986-02-01)
The effects of ten organotins on rat platelet aggregation mechanisms were examined. Bis(tri-n-butyltin)oxide was the most potent inhibitor of both ADP- and collagen-induced aggregation, and it was the only organotin that directly induced aggregation. It also increased the latent period
K Grote et al.
Environmental research, 101(1), 81-88 (2005-09-16)
In a one-generation reproductive study, the fungicidal compound triphenyltin hydroxide (fentin) was administered to adult Japanese quail for 6 weeks at dietary levels of 3 and 30 ppm. Reproduction was significantly impaired in the high-dose group. The principal adverse finding
L G Costa
Toxicology and applied pharmacology, 79(3), 471-479 (1985-07-01)
Trimethyltin, its tetra-, di-, and monomethyl analogs, inorganic tin (Sn II and Sn IV), triethyltin, tripropyltin, tributyltin, and triphenyltin were tested for their ability in inhibiting the uptake of gamma-[3H]aminobutyric acid (GABA) into mouse forebrain synaptosomes in vitro. All organotins
A biochromatographic technique for the quantitative estimation of triphenyltin fungicides.
M Adinarayana et al.
Journal of chromatography, 435(1), 210-218 (1988-01-01)

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