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364843

Sigma-Aldrich

Ethyl glycolate

98%

Synonym(s):

2-Hydroxyacetic acid ethyl ester, Ethyl 2-hydroxyacetate, Ethyl hydroxyacetate

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About This Item

Linear Formula:
HOCH2CO2C2H5
CAS Number:
623-50-7
Molecular Weight:
104.10
EC Number:
210-798-4
MDL number:
MFCD00021970
UNSPSC Code:
12352100
PubChem Substance ID:
24862461
NACRES:
NA.22

assay

98%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

158-159 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)CO

InChI

1S/C4H8O3/c1-2-7-4(6)3-5/h5H,2-3H2,1H3

InChI key

ZANNOFHADGWOLI-UHFFFAOYSA-N

Related Categories

General description

Ethyl glycollate is an ester. Microwave spectra of ethyl glycollate and its deuterated species has been reported.

Application

Ethyl glycollate is an important building block for the preparation of medicinal compounds and agrochemicals. It may be used:
  • as starting reagent in the synthesis of 2-ferrocenylfuran
  • as substrate during the polycondensation of α-hydroxy acids by enzymes and polyethylene glycol (PEG)-modified enzymes
  • in the synthesis of poly(PDL-GA) copolymers, via enzymatic catalysis

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Polycondensation of a-hydroxy acids by enzymes or PEG-modified enzymes in organic media.
Ohya Y, et al.
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 32(2), 179-190 (1995)
Aldrichimica Acta, 23, 51-51 (1990)
Microwave spectrum, conformational equilibrium and Ab initio computations for ethyl glycolate.
Marstokk KM and M?llendal H.
Acta Chirurgica Scandinavica. Supplementum, 46, 1183-1183 (1992)
Synthesis of ferrocenyl-substituted heterocycles: the beneficial effect of the microwave irradiation.
Puciova M, et al.
Collection of Czechoslovak Chemical Communications, 59(1), 175-185 (1994)
Copolymers of ethyl glycolate and ?-pentadecalactone: Enzymatic synthesis and solid-state characterization.
Mazzocchetti L, et al.
Eur. Polymer J., 47(5), 942-948 (2011)

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