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Sigma-Aldrich

(2-Hydroxyethyl)-β-cyclodextrin

extent of labeling: ~0.7 mol per mol cellulose

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Synonym(s):
2-HE-β-CD, 2-hydroxyethyl-β-CD, HP-β-CD
CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.22

form

powder

Quality Level

optical activity

[α]20/D 120 to 140°, c = 1 in H2O

extent of labeling

~0.7 mol per mol cellulose

mp

260 °C (dec.) (lit.)

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General description

(2-Hydroxyethyl)-β-cyclodextrin is a chemically modified, hydroxyalkylated derivative of cyclodextrin that finds potential use mainly in cosmetics application.

Application

(2-Hydroxyethyl)-β-cyclodextrin may be used as a chiral selector to resolve cathinone derivatives, lactic acid and oxybutynin enantiomers by capillary electrophoresis (CE), and high performance liquid chromatography (HPLC) techniques.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Design of Nanostructures for Versatile Therapeutic Applications
Pharmaceutical Nanotechnology (2018)
Cyclodextrin Fundamentals, Reactivity and Analysis
Environmental Chemistry for a Sustainable World (2018)
Paweł Mateusz Nowak et al.
Electrophoresis, 39(19), 2406-2409 (2018-07-13)
Methcathinone (ephedrone), 4-methylmethcathinone (mephedrone), and 3-methylmethcathinone (metaphedrone) are toxicologically-important cathinone derivatives used commonly as designer drugs. In this work we show the first method allowing to separate simultaneously all these molecules in a chiral medium, ensuring good resolution between all
Equilibrium studies on enantioselective extraction of oxybutynin enantiomers by hydrophilic beta-cyclodextrin derivatives
Tang K, et al.
AIChE Journal, 57(11), 3027-3036 (2011)
L Saavedra et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 766(2), 235-242 (2002-02-05)
The optimization of the separation conditions of the two optical isomers of lactic acid by a factorial design is reported. Initially, different chiral selectors were systematically investigated and then a experimental design with three quantitative factors (cyclodextrin concentration and background

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