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Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T)

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Synonym(s):
N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC
Empirical Formula (Hill Notation):
C8H17N3
CAS Number:
Molecular Weight:
155.24
Beilstein/REAXYS Number:
507429
EC Number:
MDL number:
PubChem Substance ID:

assay

≥97.0% (T)

form

liquid

reaction suitability

reaction type: Coupling Reactions

refractive index

n20/D 1.461

density

0.877 g/mL at 20 °C (lit.)

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

InChI key

LMDZBCPBFSXMTL-UHFFFAOYSA-N

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1 of 4

This Item
E6383E775003450
form

liquid

form

crystalline

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

reaction suitability

reaction type: Coupling Reactions

reaction suitability

-

reaction suitability

-

reaction suitability

-

refractive index

n20/D 1.461

refractive index

-

refractive index

-

refractive index

-

General description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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