47674

Fmoc-Gln(Trt)-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(s): N_α-Fmoc-N_δ-trityl-L-glutamine
• Empirical Formula (Hill Notation): C₃₉H₃₄N₂O₅
• CAS Number: 132327-80-1
• Molecular Weight: 610.70
• Beilstein/REAXYS Number: 4343953
• MDL number: MFCD00077056
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651077
• NACRES: NA.26

Properties

• product name: Fmoc-Gln(Trt)-OH, ≥98.0% (HPLC)
• assay: ≥98.0% (HPLC)
• form: powder
• optical activity: [α]/D -14.0±1.5°, c = 1% in DMF
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• SMILES string: OC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
• InChI: 1S/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m0/s1
• InChI key: WDGICUODAOGOMO-DHUJRADRSA-N

Description

General description

Fmoc-Gln(Trt)-OH also known as Nα-Fmoc-Nδ-trityl-L-glutamine, a Fmoc protected amino acid derivative used as a reagent in the synthesis of peptides. As glutamine is protected with a trityl group, unwanted substitute products in the reactions can be prevented.

Application

Fmoc-Gln(Trt)-OH is used as a starting material in the Fmoc solid phase peptide synthesis of fellutamide B and N-octanoyl analog of fellutamide B.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)