518786

4-Hydroxy-3-methoxyphenylboronic acid pinacol ester

98%

• Synonym(s): 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, 4-Hydroxy-3-methoxyphenylboronic acid, pinacol cyclic ester
• Empirical Formula (Hill Notation): C₁₃H₁₉BO₄
• CAS Number: 269410-22-2
• Molecular Weight: 250.10
• MDL number: MFCD02093723
• UNSPSC Code: 12352103
• PubChem Substance ID: 24874046
• NACRES: NA.22

Properties

• assay: 98%
• mp: 105-109 °C (lit.)
• SMILES string: COc1cc(ccc1O)B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C13H19BO4/c1-12(2)13(3,4)18-14(17-12)9-6-7-10(15)11(8-9)16-5/h6-8,15H,1-5H3
• Inchi Key: WFSJROCEOJANPD-UHFFFAOYSA-N

Description

Application

4-Hydroxy-3-methoxyphenylboronic acid pinacol ester can be used as a reactant:

• In the Suzuki-Miyaura cross-coupling reaction.
• To prepare ethylidenedihydroindolones as potential neoplastic agents.
• To synthesize 5,6-dihydropyrrolo[2,1-b]isoquinoline derivatives, which can be utilized as scaffolds to prepare lamellarin analogs via regioselective bromination and Suzuki cross-coupling reactions.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves