65671

(R)-1-{(R_P)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine

≥97%

• Synonym(s): (1S)-1-[(1R)-1-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ethyl]-2-[2-(diphenylphosphino)phenyl]ferrocene, Walphos SL-W001-2
• Empirical Formula (Hill Notation): C₄₆H₃₂F₁₂FeP₂
• CAS Number: 387868-06-6
• Molecular Weight: 930.52
• MDL number: MFCD08561122
• UNSPSC Code: 12352101
• PubChem Substance ID: 24884219
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥97%
• optical purity: ee: ≥99%
• SMILES string: [Fe].[CH]1[CH][CH][CH][CH]1.C[C@@H]([C]2[CH][CH][CH][C]2c3ccccc3P(c4ccccc4)c5ccccc5)P(c6cc(cc(c6)C(F)(F)F)C(F)(F)F)c7cc(cc(c7)C(F)(F)F)C(F)(F)F
• InChI: 1S/C41H27F12P2.C5H5.Fe/c1-25(34-16-10-17-35(34)36-15-8-9-18-37(36)55(30-11-4-2-5-12-30)31-13-6-3-7-14-31)54(32-21-26(38(42,43)44)19-27(22-32)39(45,46)47)33-23-28(40(48,49)50)20-29(24-33)41(51,52)53;1-2-4-5-3-1;/h2-25H,1H3;1-5H;/t25-;;/m0../s1
• InChI key: LKNKYBWIZNAXBY-WLOLSGMKSA-N

Description

General description

The product is an air-stable and non-hygroscopic Solvias chiral phosphine ligand.

Application

Walphos SL-W001-2, in the presence of a ruthenium catalyst may be used as a ligand in the following processes:

• Asymmetric hydrogenation of IPCA-D, a cinnamic acid derivative.
• Addition of 3,5-difluorophenylketimine to 4-methoxyphenylboronic acid to form the corresponding tertiary substituted cyclic sulfamate derivative with high enantioselctivity.2

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

sold in collaboration with Solvias AG

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)