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DL-α-Tocopherol methoxypolyethylene glycol succinate solution

greener alternative

2 wt. % in H2O

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Synonym(s):
TPGS-750-M
Linear Formula:
(C2H4O)nC34H56O5
CAS Number:

form

liquid

Quality Level

reaction suitability

reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis

reagent type: surfactant

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

concentration

2 wt. % in H2O

refractive index

n20/D 1.336

density

1.002 g/mL at 25 °C

greener alternative category

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1 of 4

This Item
576680503029992
vibrant-m

57668

D-α-Tocopherol polyethylene glycol 1000 succinate

Premium Grade
vibrant-m

05030

Sodium dodecyl sulfate solution

Premium Grade
vibrant-m

29992

DL-α-Tocopherol acetate

-
form

liquid

form

powder, crystals or chunks

form

liquid

form

liquid

density

1.002 g/mL at 25 °C

density

-

density

1.03 g/mL at 20 °C

density

0.96 g/mL at 20 °C (lit.)

reaction suitability

reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis, reagent type: surfactant

reaction suitability

-

reaction suitability

-

reaction suitability

-

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

concentration

2 wt. % in H2O

concentration

≥25% (ALPHA TOCOPHEROL)

concentration

20% in H2O

concentration

-

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.

Included among the possible reactions are:
  • Olefin metathesis
  • Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
  • C-H activation reactions

Second generation amphiphile for cross-coupling reactions in water

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

Related product

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Customers Also Viewed

Articles

Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.

Prof. Bruce Lipshutz's labs developed surfactants for efficient water-based reactions, offering a greener alternative to solvent-based processes.

Protocols

TPGS-750-M, a second generation surfactant, may be used in water at room temperature for Buchwald-Hartwig Amination, Suzuki-Miyaura reactions, Heck reactions, Sonogashira reactions, Negishi reactions, and olefin metathesis.

Related Content

Prof. Bruce Lipshutz and co-workers have developed designer surfactants to allow several classes of transformations (e.g. Suzuki-Miyaura, Olefin Metathesis, 1,4-Addition to Enones, etc.) to be performed in water.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service