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Key Documents

855294

Sigma-Aldrich

8-Aminooctanoic acid

99%

Synonym(s):

ω-Aminocaprylic acid

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About This Item

Linear Formula:
NH2(CH2)7COOH
CAS Number:
Molecular Weight:
159.23
Beilstein/REAXYS Number:
1756493
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

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Quality Level

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

194 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NCCCCCCCC(O)=O

InChI

1S/C8H17NO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7,9H2,(H,10,11)

InChI key

UQXNEWQGGVUVQA-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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T P Hicks et al.
Neuroscience letters, 57(3), 295-299 (1985-06-24)
The 8-carbon chain analogue of gamma-aminobutyric acid (GABA), omega-aminocaprylic acid (omega-AC), was administered to single cortical neurones of rat by microiontophoresis and its effect on cell firing compared to the effect elicited by GABA. The spontaneous and glutamate-elicited firing rates
A J Dobson et al.
Acta crystallographica. Section C, Crystal structure communications, 54 ( Pt 7), 969-972 (1998-09-18)
The title acid, 8-aminooctanoic acid, C8H17NO2, crystallized in the centrosymmetric space group P2(1)/n in the zwitterionic form. The three H atoms involved in hydrogen bonding are ordered. The five intermolecular N-H...O hydrogen bonds have N...O distances ranging from 2.752 (2)
Eun-Mi Kim et al.
Nuclear medicine and biology, 36(4), 371-378 (2009-05-09)
c-Met is a receptor tyrosine kinase involved in tumor cell growth, invasion, metastases and angiogenesis. Overexpression of c-Met is frequently observed in several tumor types. Here, we report the in vitro cell-binding properties and biodistribution and SPECT/CT imaging in glioma
Charles Evans et al.
BMC chemical biology, 10, 2-2 (2010-02-24)
NAD+ is a coenzyme for hydride transfer enzymes and a substrate for sirtuins and other NAD+-dependent ADPribose transfer enzymes. In wild-type Saccharomyces cerevisiae, calorie restriction accomplished by glucose limitation extends replicative lifespan in a manner that depends on Sir2 and
E J Demant
Biochimica et biophysica acta, 1304(1), 43-55 (1996-11-11)
Using a hydrophobic 8-aminooctanoic acid cross-linker, the pH-indicator dye 7-hydroxycoumarin-4-acetic acid (7-HCA) is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups. A highly stable and water-soluble complex (BSA-HCA) with a 1:4 molar stoichiometry is

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