A59522
2-Aminoindan hydrochloride
98%
Synonym(s):
2-Indanamine hydrochloride
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C9H11N · HCl
CAS Number:
Molecular Weight:
169.65
Beilstein/REAXYS Number:
3913700
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
form
crystals
mp
245-247 °C (lit.)
SMILES string
Cl[H].NC1Cc2ccccc2C1
InChI
1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H
InChI key
XEHNLVMHWYPNEQ-UHFFFAOYSA-N
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Application
Prepared from 2-indanols via azide displacement and subsequent hydrogenation.
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Loanda R Cumba et al.
The Analyst, 140(16), 5536-5545 (2015-06-24)
"Synthacaine" is a New Psychoactive Substance which is, due to its inherent psychoactive properties, reported to imitate the effects of cocaine and is therefore consequently branded as "legal cocaine". The only analytical approach reported to date for the sensing of
H Wikström et al.
Journal of medicinal chemistry, 30(7), 1115-1120 (1987-07-01)
Conformational analyses on differently substituted 2-aminoindans of significant pharmacological interest were carried out by the molecular mechanics method (MM2). An X-ray structure of (R)-4-methoxy-2-aminoindan has shown the ammonium nitrogen [-)-D-tartaric acid salt) in an axial position. From comparison with other
S P Arnerić et al.
Archives internationales de pharmacodynamie et de therapie, 258(1), 84-99 (1982-07-01)
The ability of 2-aminotetralins (2-ATs), 2-aminoindanes (2-AIs), morphine (M) and clonidine (CLON) to alter neuroeffector transmission was studied on field-stimulated (FS) guinea-pig ilea (GPI). The activity of these compounds to inhibit K+, histamine (H), actylcholine (ACh), nicotine (Nic) and serotonin
J A Pérez et al.
Arzneimittel-Forschung, 47(11), 1208-1210 (1998-01-16)
Amino substitution of rigid forms of dopamine 4,5-dihydroxy-2-aminoindan and 5,6-dihydroxy-2-aminoindan with aralkyl functionalities were carried out to investigate the role of such structural modifications upon cardiac inotropic-chronotropic activity. Compounds synthesized demonstrated a modest inotropic selectivity, while one of them, described
Sebastian A Andujar et al.
Bioorganic & medicinal chemistry, 16(6), 3233-3244 (2008-01-02)
Brain dopaminergic system has a crucial role in the etiology of several neuropsychiatric disorders, including Parkinson's disease, depression, and schizophrenia. Several dopaminergic drugs are used to treat these pathologies, but many problems are attributed to these therapies. Within this context
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