C5106

(Carbethoxymethylene)triphenylphosphorane

95%

• Synonym(s): (Ethoxycarbonylmethylene)triphenylphosphorane, Ethyl (triphenylphosphoranylidene)acetate
• Linear Formula: (C₆H₅)₃P=CHCO₂CH₂CH₃
• CAS Number: 1099-45-2
• Molecular Weight: 348.37
• Beilstein/REAXYS Number: 754639
• EC Number: 214-151-7
• MDL number: MFCD00009183
• UNSPSC Code: 12352108
• PubChem Substance ID: 24892754
• NACRES: NA.22

Properties

• assay: 95%
• form: crystals
• reaction suitability: reaction type: C-C Bond Formation
• mp: 128-130 °C (lit.)
• Storage temp.: 2-8°C
• SMILES string: CCOC(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H21O2P/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,2H2,1H3
• Inchi Key: IIHPVYJPDKJYOU-UHFFFAOYSA-N

Description

Application

(Carbethoxymethylene)triphenylphosphorane is a Horner-Wittig reagent generally used in Horner−Wadsworth−Emmons (HWE) reaction. It is used as a reagent in the total synthesis of compounds such as (−)-oseltamivir, (+)-nakadomarin A and (−)-dictyostatin.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)