E14578

Ethyl bromopyruvate

technical grade, 90%

• Synonym(s): β-Bromopyruvic acid ethyl ester, 3-Bromo-2-(oxo)propionic acid ethyl ester, 3-Bromo-2-oxopropanoic acid ethyl ester, 3-Bromopyruvic acid ethyl ester, Bromopyruvic acid ethyl ester, Ethyl α-bromopyruvate, Ethyl 3-bromo-2-oxopropanoate, Ethyl 3-bromo-2-oxopropionate, Ethyl 3-bromopyruvate
• Linear Formula: BrCH₂COCOOC₂H₅
• CAS Number: 70-23-5
• Molecular Weight: 195.01
• Beilstein/REAXYS Number: 1760158
• EC Number: 200-729-6
• MDL number: MFCD00000204
• UNSPSC Code: 12352100
• PubChem Substance ID: 24894412
• NACRES: NA.22

Properties

• grade: technical grade
• Quality Level: 100
• assay: 90%
• refractive index: n20/D 1.469 (lit.)
• bp: 98-100 °C/10 mmHg (lit.)
• density: 1.554 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCOC(=O)C(=O)CBr
• InChI: 1S/C5H7BrO3/c1-2-9-5(8)4(7)3-6/h2-3H2,1H3
• InChI key: VICYTAYPKBLQFB-UHFFFAOYSA-N

Description

General description

Ethyl bromopyruvate, also known as Bromopyruvic acid ethyl ester, is an alkyl-substituted α-bromoketones, that is commonly used as a building block in various organic reaction, such as in the synthesis of 1,3-Oxazoline-2-thiones and 3-bromoimidazopyridines.

Application

Ethyl bromopyruvate is used as an electrophile:

• for the synthesis of thiazoles with substituted benzothioamides

Also, employed in a synthesis of thioxothiazolidines from primary amines and carbon disulfide.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 210.2 °F - closed cup
• flash_point_c: 99 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter