H36001

Vanillic acid

97%

• Synonym(s): 4-Hydroxy-3-methoxybenzoic acid
• Linear Formula: HOC₆H₃(OCH₃)CO₂H
• CAS Number: 121-34-6
• Molecular Weight: 168.15
• Beilstein/REAXYS Number: 2208364
• EC Number: 204-466-8
• MDL number: MFCD00002551
• UNSPSC Code: 12352100
• PubChem Substance ID: 24895581
• NACRES: NA.22

Properties

• assay: 97%
• mp: 208-210 °C (lit.)
• SMILES string: COc1cc(ccc1O)C(O)=O
• InChI: 1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)
• InChI key: WKOLLVMJNQIZCI-UHFFFAOYSA-N

Description

General description

Vanillic acid, also known as 4-Hydroxy-3-methoxybenzoic acid, is a phenolic molecule, commonly used as a building block in the synthesis of surfactants, flavorants, odorants, and plasticizers.

Application

• Vanillin Synthesis from Vanillic Acid: Research focused on engineering the activity and thermostability of a carboxylic acid reductase for converting vanillic acid to vanillin, providing insights into biotechnological applications for flavor and fragrance industries (Ren et al., 2024).
• Antioxidant Properties in Food Preservation: The antioxidant properties of vanillic acid were evaluated in a study on the preservation of postharvest quality and physicochemical properties of broccoli, suggesting its potential in extending the shelf life and nutritional quality of fresh produce (Kibar et al., 2024).
• Biological Synthesis of Vanillin: A comprehensive review discussed various biological methods for synthesizing vanillin from vanillic acid, emphasizing its application in enhancing natural flavor profiles in the food sector (Venkataraman et al., 2024).

Vanillic acid is used as a starting material in the synthesis of:

• aliphatic-aromatic polymers with good thermal stability and degradability
• novel polyesters via esterification and etherification reaction

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)