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Key Documents

S3003

Sigma-Aldrich

Sesamol

98%

Synonym(s):

3,4-(Methylenedioxy)phenol, 5-Benzodioxolol

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About This Item

Empirical Formula (Hill Notation):
C7H6O3
CAS Number:
Molecular Weight:
138.12
Beilstein/REAXYS Number:
127405
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

mp

62-65 °C (lit.)

SMILES string

Oc1ccc2OCOc2c1

InChI

1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2

InChI key

LUSZGTFNYDARNI-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Tian Yuan et al.
Journal of agricultural and food chemistry, 67(22), 6190-6201 (2019-05-24)
Sesamol, an antioxidant lignan from sesame oil, possesses neuroprotective bioactivities. The present work was aimed to elucidate the systemic protective effects of sesamol on cognitive deficits and to determine the possible link between gut and brain. Wildtype and ApoE-/- mice
Soheila Kashanian et al.
Molecular biology reports, 40(2), 1173-1179 (2012-10-17)
The interaction of native calf thymus DNA (CT-DNA) with sesamol (3,4-methylenedioxyphenol) in Tris-HCl buffer at neutral pH 7.4 was monitored by absorption spectrophotometry, viscometry and spectrofluorometry. It is found that sesamol molecules could interact with DNA outside and/or groove binding
Yung-Chang Lu et al.
Journal of agricultural and food chemistry, 59(9), 4969-4978 (2011-03-25)
Overexpression of matrix metalloproteinases (MMPs) is a major pathological factor causing cartilage destruction in osteoarthritis (OA). This study aimed to investigate the effects and mechanisms of sesamol on expression of MMPs in activated chondrosarcoma cells. Sesamol significantly attenuated TNF-α- and
Ashok Kumar Sharma et al.
The Journal of nutritional biochemistry, 23(11), 1482-1489 (2012-03-09)
Increased oxidative stress and inflammation in obesity are the central and causal components in the pathogenesis and progression of cardiometabolic syndrome (CMetS). The aim of the study was to determine the potential role of sesamol (a natural powerful antioxidant and
Chao-Chien Chang et al.
Journal of biomedical science, 18, 93-93 (2011-12-16)
Platelet activation is relevant to a variety of coronary heart diseases. Our previous studies revealed that sesamol possesses potent antiplatelet activity through increasing cyclic AMP formation. Although platelets are anucleated cells, they also express the transcription factor, NF-κB, that may

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