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Key Documents

W390208

Sigma-Aldrich

Tea tree oil

FG

Synonym(s):

Melaleuca alternifolia

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About This Item

CAS Number:
FEMA Number:
3902
MDL number:
UNSPSC Code:
12164502
NACRES:
NA.21

biological source

Melaleuca alternifolia

Quality Level

grade

FG
Halal
Kosher

reg. compliance

EU Regulation 1334/2008 & 872/2012

optical activity

[α]20/D +9.4°, neat

origin

Australia origin

refractive index

n20/D 1.478 (lit.)

bp

165 °C (lit.)

density

0.898 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

spicy; warm

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Application


  • Comprehensive antifungal investigation of natural plant extracts against Neosartorya spp. (Aspergillus spp.) of agriculturally significant microbiological contaminants and shaping their metabolic profile.: This research examines various plant extracts, including tea tree oil, for their effectiveness in inhibiting fungal pathogens in agriculture, which could lead to safer crop preservation and disease management strategies (Frąc et al., 2024).

  • Comparison of Approaches for Authentication of Commercial Terpinen-4-ol-type Tea Tree Oils Using Chiral GC/MS.: The paper discusses methods to authenticate and ensure the purity of commercial tea tree oil, crucial for maintaining its therapeutic efficacy and safety (Downey et al., 2024).

  • Ovicidal, larvicidal and adulticidal activity of black pepper (Piper nigrum L.) essential oil and tea tree oil (Melaleuca alternifolia) against Haemonchus contortus.: This research evaluates the efficacy of tea tree oil in combination with black pepper oil as a natural remedy for controlling parasitic worms, suggesting an eco-friendly alternative to chemical anthelmintics (El-Dakhly et al., 2024).

Preparation Note

Extraction method: steam distillation

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

147.2 °F

flash_point_c

64 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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Hyun Koo et al.
Journal of Korean medical science, 27(12), 1574-1579 (2012-12-21)
The purpose of this study was to evaluate the relation between ocular discomfort and ocular Demodex infestation, and therapeutic effects of tea tree oil (TTO) in Demodex blepharitis patients. Three hundred and thirty-five patients with ocular discomfort were evaluated for
Demelza J Ireland et al.
Journal of dermatological science, 67(2), 120-129 (2012-06-26)
Melaleuca alternifolia (tea tree) oil (TTO) applied topically in a dilute (10%) dimethyl sulphoxide (DMSO) formulation exerts a rapid anti-cancer effect after a short treatment protocol. Tumour clearance is associated with skin irritation mediated by neutrophils which quickly and completely
G Tirabassi et al.
Journal of endocrinological investigation, 36(1), 50-54 (2012-12-06)
Hirsutism is defined as the presence of excessive terminal hair in androgen-dependent areas of a woman's body. Regarding this it has been suggested that Lavender and Tea tree oils may have antiandrogenic activities. To evaluate therapy based on Lavender and
Kunj G Patel et al.
The West Virginia medical journal, 109(3), 16-18 (2013-06-27)
We present a case of blepharitis with symptoms lasting two years in duration and refractory to a host of prior medical treatments, including antibiotics, corticosteroids, cyclosporine, and baby shampoo. We recognized the clinical presentation as pathogomonic for demodicosis caused by
Jesus A Cuaron et al.
Phytotherapy research : PTR, 27(3), 390-396 (2012-05-24)
Tea tree oil (TTO) is a steam distillate of Melaleuca alternifolia that demonstrates broad-spectrum antibacterial activity. This study was designed to document how TTO challenge influences the Staphylococcus aureus transcriptome. Overall, bioinformatic analyses (S. aureus microarray meta-database) revealed that both

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