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830855P

Avanti

16:0 PA

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phosphate (sodium salt); DPPA; PA(16:0/16:0); 110614

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About This Item

Empirical Formula (Hill Notation):
C35H68O8PNa
CAS Number:
169051-60-9
Molecular Weight:
670.87
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dipalmitoyl-sn-glycero-3-phosphate (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (830855P-200mg)
pkg of 1 × 25 mg (830855P-25mg)
pkg of 1 × 500 mg (830855P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C35H69O8P.2Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(36)41-31-33(32-42-44(38,39)40)43-35(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;;/h33H,3-32H2,1-2H3,(H2,38,39,40);;/q;2*+1/p-2/t33-;;/m1../s1

InChI key

NFRFUGBXJTXTMZ-QYKZUBHNSA-L

General description

Phosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D.

Application

16:0 PA may be used as lipid standards for the quantification of the lipid species released from E-SYT2 expressed in mammalian cells. It may also be used in the synthesis of the methylene blue microbubbles.

Biochem/physiol Actions

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 16:0 PA/DPPA can improve the bactericidal effect of eugenol.

Packaging

20 mL Clear Glass Screw Cap Vial (830855P-500mg)
5 mL Amber Glass Screw Cap Vial (830855P-200mg)
5 mL Amber Glass Screw Cap Vial (830855P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Methylene blue microbubbles as a model dual-modality contrast agent for ultrasound and activatable photoacoustic imaging
Jeon M, et al.
Journal of Biomedical Optics, 19(1), 016005-016005 (2014)
Lorissa J Smulan et al.
Cell reports, 16(1), 9-18 (2016-06-21)
Lipogenesis requires coordinated expression of genes for fatty acid, phospholipid, and triglyceride synthesis. Transcription factors, such as SREBP-1 (Sterol regulatory element binding protein), may be activated in response to feedback mechanisms linking gene activation to levels of metabolites in the
Critical synergistic concentration of lecithin phospholipids improves the antimicrobial activity of eugenol against Escherichia coli
Zhang H, et al.
Applied and Environmental Microbiology, 83(21), e01583-e01517 (2017)
Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer
Schauder CM, et al.
Nature, 510(7506), 552-552 (2014)
Esra Ilhan-Ayisigi et al.
Macromolecular bioscience, 20(6), e2000084-e2000084 (2020-04-30)
In this study, the neoplastic drug frequently used in the treatment of lung cancer, carboplatin is loaded to microbubbles via a microfluidic platform. In order to increase the drug loading capacity of microbubbles, carboplatin is encapsulated into alginate polymer layer.
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