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850465P

Avanti

18:0-16:0 PC

1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder

Synonym(s):

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; SPPC; PC(18:0/16:0)

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About This Item

Empirical Formula (Hill Notation):
C42H84NO8P
CAS Number:
59403-53-1
Molecular Weight:
762.09
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850465P-200mg)
pkg of 1 × 25 mg (850465P-25mg)
pkg of 1 × 500 mg (850465P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850465P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

General description

Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup.

Application

18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • in bilayer membranes to study the thermodynamic properties of phase transitions
  • as a carrier in unilamellar vesicles to evaluate the fragmentation of hydroperoxy endoperoxide 13-HP-Endo-PC in a model membrane
  • as a lipid standard in liquid chromatography−mass spectrometry analysis

Biochem/physiol Actions

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.

Packaging

20 mL Clear Glass Screw Cap Vial (850465P-500mg)
5 mL Amber Glass Screw Cap Vial (850465P-200mg)
5 mL Amber Glass Screw Cap Vial (850465P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Xiaodong Gu et al.
Chemical research in toxicology, 24(7), 1080-1093 (2011-05-17)
Biologically active phospholipids that incorporate an oxidatively truncated acyl chain terminated by a γ-hydroxyalkenal are generated in vivo. The γ-hydroxyalkenal moiety protrudes from lipid bilayers like whiskers that serve as ligands for the scavenger receptor CD36, fostering endocytosis, e.g., of
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Masaki Goto et al.
Biochimica et biophysica acta, 1778(4), 1067-1078 (2008-01-15)
The bilayer phase transitions of palmitoylstearoyl-phosphatidylcholine (PSPC), diheptadecanoyl-PC (C17PC) and stearoylpalmitoyl-PC (SPPC) which have the same total carbon numbers in the two acyl chains were observed by differential scanning calorimetry and high-pressure optical method. As the temperature increased, these bilayers
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features
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