860635P
Avanti
C12 Dihydroceramide (d18:0/12:0)
Avanti Research™ - A Croda Brand 860635P, powder
Synonym(s):
N-lauroyl-D-erythro-sphinganine
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About This Item
Empirical Formula (Hill Notation):
C30H61NO3
CAS Number:
Molecular Weight:
483.81
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 5 mg (860635P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860635P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
Application
C12 Dihydroceramide has been used as an internal standard for quantification of dihydroceramides in adipose tissue by liquid chromatography - tandem mass spectrometry (LC-MS-MS).
Packaging
5 mL Amber Glass Screw Cap Vial (860635P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Product No.
Description
Pricing
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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George D Mcilroy et al.
Biochemical pharmacology, 100, 86-97 (2015-11-26)
Fenretinide (FEN) is a synthetic retinoid that inhibits obesity and insulin resistance in high-fat diet (HFD)-fed mice and completely prevents 3T3-L1 pre-adipocyte differentiation. The aim of this study was to determine the mechanism(s) of FEN action in 3T3-L1 adipocytes and
Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue
Mcilroy GD, et al.
Biochemical Pharmacology, 100, 86-97 (2016)
Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
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