D-048
N-Desmethylclozapine solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
shipped in
wet ice
storage temp.
−20°C
SMILES string
Clc1ccc2Nc3ccccc3C(=Nc2c1)N4CCNCC4
InChI
1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2
InChI key
JNNOSTQEZICQQP-UHFFFAOYSA-N
General description
Application
- Pharmacokinetic analysis of clozapine and N-Desmethylclozapine: A study conducted by Mach et al. (2024) analyzed clinical and pharmacological factors that influence serum levels of clozapine and its metabolite N-Desmethylclozapine, offering insights into dosing strategies and metabolic pathways relevant to schizophrenia treatment (Mach et al., 2024).
- Chromatographic profiling for clozapine and its metabolites: Hrichi et al. (2024) reviewed chromatographic methods for analyzing antipsychotic drugs, including clozapine and N-Desmethylclozapine, to improve the accuracy of pharmacokinetic studies and enhance drug monitoring capabilities (Hrichi et al., 2024).
- Influence of lifestyle factors on clozapine metabolism: Research by Flanagan et al. (2024) explored the impact of coffee and chocolate ingestion on the plasma concentrations of clozapine and its metabolite N-Desmethylclozapine, providing data crucial for understanding how dietary habits affect antipsychotic drug levels (Flanagan et al., 2024).
Legal Information
related product
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
wgk_germany
WGK 1
flash_point_f
49.5 °F
flash_point_c
9.7 °C
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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