I-032

Ibuprofen-D₃ solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₃H₁₅D₃O₂
• CAS Number: 121662-14-4
• Molecular Weight: 209.30
• MDL number: MFCD06658737
• UNSPSC Code: 41116107
• PubChem Substance ID: 329815305
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: CC(C)CC1=CC=C(C(C([2H])([2H])[2H])C(O)=O)C=C1
• InChI: 1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/i3D3
• InChI key: HEFNNWSXXWATRW-HPRDVNIFSA-N

Description

General description

An internal standard suitable for use in LC/MS and GC/MS applications such as clinical toxicology, forensic analysis, pharmaceutical research, and isotope dilution methods. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation. Ibuprofen functions as an unspecific COX inhibitor.

Application

• Internal Standard in Pharmacokinetic Research: Ibuprofen-D₃ solution is utilized as a stable-labeled internal standard in pharmacokinetic research, particularly in SIL-IS LC-MS/MS methods for analyzing ibuprofen in human plasma. This application ensures accurate measurement and consistent data quality in bioanalytical studies, facilitating the detailed assessment of drug behavior in the body (Wang et al., 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup