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1335508

USP

Ibuprofen

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
p-Isobutylhydratropic acid, Benzeneacetic acid, α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid
Empirical Formula (Hill Notation):
C13H18O2
CAS Number:
15687-27-1
Molecular Weight:
206.28
MDL number:
MFCD00010393
UNSPSC Code:
41116107
PubChem Substance ID:
329750144
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ibuprofen

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChI key

HEFNNWSXXWATRW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ibuprofen USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard preparation, standard and standard stock solution for performance tests, assay, identification, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Diphenhydramine Hydrochloride and Ibuprofen Capsules
  • Ibuprofen and Pseudoephedrine Hydrochloride Tablets

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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PHR2122

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PHR2143

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PHR2142

Ibuprofen 1,3-Butylene Glycol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

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Ibuprofen impurity B, British Pharmacopoeia (BP) Reference Standard

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PHR2483

4-Acetylbenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2138

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PHR2125

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PHR2127

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PHR2129

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PHR2130

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PHR2134

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PHR2135

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PHR2132

2-[4-(2-Hydroxy-2-methylpropyl)-phenyl]propanoic Acid, certified reference material, pharmaceutical secondary standard

PHR2137

Ibuprofen Methyl Ester, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2133

Ibuprofen Intermediate, certified reference material, pharmaceutical secondary standard

PHR2126

2-Hydroxypropyl 2-(4-Isobutylphenyl)-propanoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2269

4-Isobutylbenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

Certificates of Analysis (COA)

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Sigma-Aldrich

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