05-1113

Anti-Harmartin (TSC1) Antibody

ascites fluid, from mouse

• Synonym(s): Tuberous sclerosis 1 protein, tuberous sclerosis 1, tumor suppressor
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: monoclonal
• species reactivity: human, rat
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• isotype: IgG1
• UniProt accession no.: Q92574
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TSC1(7248)

Description

General description

Harmartin is the gene product of tuberous sclerosis-1 (TSC1). It is thought to have a tumor suppression function and also augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination.

Specificity

This antibody recognizes Harmartin

Immunogen

Recombinant protein from human Harmartin

Application

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Harmartin in human skin tissue, melanocytes.

Research Category
Signaling

Research Sub Category
PI3K, Akt, & mTOR Signaling

This Anti-Harmartin (TSC1) Antibody is validated for use in WB, IH(P) for the detection of Harmartin (TSC1).

Quality

Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected Harmartin in 10 µg of NIH/3T3 cell lysate.

Target description

Approx. 160 kDa

Linkage

Replaces: 04-426

Physical form

Ascites fluid. Liquid. Contains no preservative.

Unpurified ascites fluid

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
NIH/3T3 cell lysate

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable