07-862
Anti-phospho-PDGFRα (Tyr754) Antibody
Upstate®, from rabbit
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Synonym(s):
CD140A, MGC74795, PDGFR2, platelet-derived growth factor receptor, alpha
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pTyr754)
Gene Information
human ... PDGFRA(5156)
General description
The previously assigned protein identifier Q9UD28 has been merged into P16234. Full details can be found on the UniProt database.
Specificity
Human and Mouse PDGFRα that is phosphorylated on Tyrosine 754 and 762, respectively. Rat is predicted to react based on sequence homology.
Predicted to cross-react with rat based on 100% sequence similarity, but has not been tested.
Immunogen
Peptide corresponding to amino acid region encompassing the human phospho-PDGFRα (Tyr754).
Application
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
This Anti-phospho-PDGFRα (Tyr754) Antibody is validated for use in WB for the detection of phospho-PDGFRα (Tyr754).
Target description
170-185 kDA
Physical form
100 μL of affinity purified rabbit polyclonal IgG in buffer (PBS (without Mg2+ and Ca2+), pH 7.4 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide).
Affinity purified
Storage and Stability
2 years at -80°C.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase.
Zemskov, EA; Loukinova, E; Mikhailenko, I; Coleman, RA; Strickland, DK; Belkin, AM
The Journal of Biological Chemistry null
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