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1.00202

Supelco

N,N-Dimethylformamide

for headspace gas chromatography SupraSolv®

Synonym(s):

DMF, N,N-Dimethylmethanamide, Formic acid dimethylamide, DMF, NSC 5356

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About This Item

Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein/REAXYS Number:
605365
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-679-5
NACRES:
NA.03

agency

according to Ph. Eur.
according to USP

Quality Level

vapor density

2.5 (vs air)

vapor pressure

2.7 mmHg ( 20 °C)

product line

SupraSolv®

assay

≥99.8% (GC)

form

liquid

autoignition temp.

833 °F

potency

3010 mg/kg LD50, oral (Rat)
1500 mg/kg LD50, skin (Rabbit)

expl. lim.

15.2 %

technique(s)

GC-HS: suitable

impurities

≤0.05% Water

evapn. residue

≤3.0 mg/L

color

APHA: ≤10

refractive index

n20/D 1.430 (lit.)

pH

7 (20 °C, 200 g/L in H2O)

bp

153 °C (lit.)

mp

−61 °C (lit.)

transition temp

flash point 57.5 °C

density

0.944 g/mL (lit.)

storage temp.

2-30°C

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

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General description

SupraSolv® high-purity solvents for headspace gas chromatography (HS-GC) are developed particularly for the analysis of residual solvents (RS) in actives, excipients and drug products according to ICH (International Council for Harmonizaton of Technical Requirements for Registration of Pharmaceuticals for Human Use) Guideline Q3C “Impurities: Guideline for Residual Solvents”.

Application

Solvent for many hydrophobic organic compounds.

Features and Benefits

  • high application reliability due to the application test performed on every batch produced
  • application-oriented quality due to specified concentrations of residual solvents as defined by ICH
  • highly pure solvent with extremely low RS concentrations

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

135.5 °F - closed cup

flash_point_c

57.5 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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