1.00765

Boric acid

99.9999 Suprapur^®

• Synonym(s): Orthoboric acid, Trihydroxidoboron
• Linear Formula: H₃BO₃
• CAS Number: 10043-35-3
• Molecular Weight: 61.83
• MDL number: MFCD00011337
• UNSPSC Code: 12352301
• EC Index Number: 233-139-2
• NACRES: NB.21

Properties

• grade: for inorganic trace analysis
• Quality Level: 100
• vapor pressure: 2.6 mmHg ( 20 °C)
• assay: ≥99% (acidimetric); 99.9999%
• form: solid
• potency: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• solubility: 49.2 g/L
• density: 1.489 g/cm³ at 23 °C
• bulk density: 400‑600 kg/m³
• anion traces: chloride (Cl^-): ≤3 ppm; phosphate (PO₄^3-): ≤0.5 ppm; silicate (as SiO₂): ≤0.5 ppm; sulfate (SO₄^2-): ≤5 ppm
• cation traces: Ag: ≤0.010 ppm; Al: ≤0.050 ppm; As: ≤0.050 ppm; Au: ≤0.020 ppm; Ba: ≤0.050 ppm; Be: ≤0.010 ppm; Ca: ≤0.050 ppm; Cd: ≤0.010 ppm; Co: ≤0.010 ppm; Cr: ≤0.010 ppm; Cu: ≤0.010 ppm; Fe: ≤0.050 ppm; Ga: ≤0.050 ppm; In: ≤0.020 ppm; K: ≤0.10 ppm; Li: ≤0.010 ppm; Mg: ≤0.10 ppm; Mn: ≤0.010 ppm; Mo: ≤0.010 ppm; N: ≤0.010 ppm; Na: ≤0.050 ppm; Pb: ≤0.020 ppm; Sr: ≤0.010 ppm; Tl: ≤0.020 ppm; V: ≤0.010 ppm; Zn: ≤0.010 ppm
• SMILES string: OB(O)O
• storage temp.: 2-30°C
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Description

Application

• Systematic development of immunohistochemistry protocol for large cryosections-specific to non-perfused fetal brain.: This study by Pandurangan et al. highlights the role of boric acid in developing an optimized immunohistochemistry protocol for large cryosections of non-perfused fetal brain tissues. Boric acid is used as a buffer component to enhance antigen retrieval and staining specificity, showcasing its importance in neuroanatomical research (Pandurangan et al., 2024).


• Proteomic Analysis of Rat Duodenum Reveals the Modulatory Effect of Boron Supplementation on Immune Activity.: Zhao et al. investigate the impact of boric acid on immune activity through proteomic analysis of rat duodenum. The study demonstrates boric acids role in modulating protein expression related to immune responses, providing insights into its potential applications in immunology and nutritional biochemistry (Zhao et al., 2023).


• The impact of boron nutrient supply in mulberry (Morus alba) response to metabolomics, enzyme activities, and physiological parameters.: Zhang et al. explore the effects of boric acid on mulberry plants′ metabolic profiles, enzyme activities, and physiological parameters. This research underscores boric acids significance in plant nutrition and stress response, offering valuable data for agricultural chemistry and plant sciences (Zhang et al., 2023).

Analysis Note

Purity (metallic): ≥ 99.9999 %
Assay (acidimetric): ≥ 99.0 %
Chloride (Cl): ≤ 3 ppm
Phosphate (PO₄): ≤ 0.5 ppm
Silicate (as SiO₂): ≤ 0.5 ppm
Sulfate (SO₄): ≤ 5 ppm
Ag (Silver): ≤ 0.010 ppm
Al (Aluminium): ≤ 0.050 ppm
As (Arsenic): ≤ 0.050 ppm
Au (Gold): ≤ 0.020 ppm
Ba (Barium): ≤ 0.050 ppm
Be (Beryllium): ≤ 0.010 ppm
Ca (Calcium): ≤ 0.050 ppm
Cd (Cadmium): ≤ 0.010 ppm
Co (Cobalt): ≤ 0.010 ppm
Cr (Chromium): ≤ 0.010 ppm
Cu (Copper): ≤ 0.010 ppm
Fe (Iron): ≤ 0.050 ppm
Ga (Gallium): ≤ 0.050 ppm
In (Indium): ≤ 0.020 ppm
K (Potassium): ≤ 0.10 ppm
Li (Lithium): ≤ 0.010 ppm
Mg (Magnesium): ≤ 0.10 ppm
Mn (Manganese): ≤ 0.010 ppm
Mo (Molybdenum): ≤ 0.010 ppm
Na (Sodium): ≤ 0.050 ppm
Ni (Nickel): ≤ 0.010 ppm
Pb (Lead): ≤ 0.020 ppm
Sr (Strontium): ≤ 0.010 ppm
Tl (Thallium): ≤ 0.020 ppm
V (Vanadium): ≤ 0.010 ppm
Zn (Zinc): ≤ 0.010 ppm

Legal Information

SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360FD
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable