1.01843

tert-Butyl methyl ether

EMPLURA^®

• Synonym(s): tert-Butyl methyl ether, Methyl tert-butyl ether, MTB, MTBE
• Linear Formula: (CH₃)₃COCH₃
• CAS Number: 1634-04-4
• Molecular Weight: 88.15
• MDL number: MFCD00008812
• UNSPSC Code: 12191502
• EC Index Number: 216-653-1
• NACRES: NA.05

Properties

• vapor pressure: 268 hPa ( 20 °C)
• Quality Level: 200
• product line: EMPLURA^®
• assay: ≥99% (GC)
• form: liquid
• autoignition temp.: 460 °C
• potency: >2000 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.5-8.5 % (v/v)
• impurities: ≤0.001% Free acid (as CH₃COOH); ≤0.005% Peroxide (as H₂O₂); ≤0.05% Water
• evapn. residue: ≤0.005%
• kinematic viscosity: 0.464 cSt(20 °C)
• bp: 55.3 °C/1013 hPa
• mp: -108.6 °C
• transition temp: flash point -28 °C
• solubility: 42 g/L
• density: 0.74 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C5H12O/c1-5(2,3)6-4/h1-4H3
• InChI key: BZLVMXJERCGZMT-UHFFFAOYSA-N

Description

General description

EMPLURA^® is our low-cost alternative to high-purity qualities. With EMPLURA we offer a range of solvents for a plurality of basic applications in non-regulated industries and for less demanding applications, preparative laboratory work and cleaning purposes. EMPLURA solvents provide adequate specifications with the most important parameters.

Application

• Evidence for HOOO radicals in the formation of alkyl hydrotrioxides (ROOOH) and hydrogen trioxide (HOOOH) in the ozonation of C-H bonds in hydrocarbons.: This research used tert-Butyl methyl ether to investigate the formation of hydrotrioxides and hydrogen trioxide in the ozonation of hydrocarbons, providing insights into radical chemistry and ozonation processes (Cerkovnik et al., 2002).


• Determination of ochratoxin A in baby food by immunoaffinity column cleanup with liquid chromatography: interlaboratory study.: The study employed tert-Butyl methyl ether in the cleanup process for detecting ochratoxin A in baby food, demonstrating its effectiveness in ensuring food safety through reliable analytical methods (Burdaspal et al., 2001).


• Sensitive high-performance liquid chromatography/mass spectrometry method for determination of steviol in rat plasma.: This paper highlights the use of tert-Butyl methyl ether in developing a sensitive HPLC/MS method for analyzing steviol in biological samples, showcasing its application in pharmacokinetic and toxicological studies (Wang et al., 2004).


• Comparative fatty acid selectivity of lipases in esterification reactions with glycerol and diol analogues in organic media.: The research employed tert-Butyl methyl ether to investigate lipase selectivity in esterification reactions, illustrating its importance in biocatalysis and industrial applications of enzymatic processes (Lee & Parkin, 2000).


• Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.: This study utilized tert-Butyl methyl ether to analyze enzyme activity in cytochrome P450, demonstrating its utility in biochemical assays and the study of enzyme kinetics (Kim et al., 2005).

Analysis Note

Purity (GC): ≥ 99.0 %
Identity (IR): conforms
Free acid (as CH₃COOH): ≤ 0.001 %
Density (d 20 °C/ 4 °C): 0.740 - 0.742
Peroxide (as H₂O₂): ≤ 0.005 %
Evaporation residue: ≤ 0.005 %
Water: ≤ 0.05 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H315
• pcodes: P210 - P233 - P240 - P241 - P242 - P303 + P361 + P353
• Hazard Classifications: Flam. Liq. 2 - Skin Irrit. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: -18.4 °F - closed cup
• flash_point_c: -28 °C - closed cup