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220411

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Chenodeoxycholic Acid, Sodium Salt

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

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Synonym(s):
Chenodeoxycholic Acid, Sodium Salt
Empirical Formula (Hill Notation):
C24H39O4 · Na
CAS Number:
Molecular Weight:
414.55
MDL number:

Quality Level

assay

>95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: 20 mg/mL
aqueous buffer: soluble

cation traces

heavy metals: <10 ppm

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;/m1./s1

InChI key

WDFRNBJHDMUMBL-OICFXQLMSA-M

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Chenodeoxycholic Acid, Sodium Salt Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

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Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

solid

form

solid

form

solid

form

solid

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

−20°C

storage temp.

15-25°C

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze

solubility

water: 20 mg/mL, aqueous buffer: soluble

solubility

acetic acid: 1 mg/mL, ethanol: 1 mg/mL

solubility

ethanol: 20 mg/mL, DMSO: 30 mg/mL

solubility

water: 200 mg/mL, ethanol: soluble

General description

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets.
Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Other Notes

Rolo, A.P., et al. 2001. Biosci. Rep.21, 73.
Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
Roda, A., et al. 1990. J. Lipid Res.31, 1433.
Spivak, W., et al. 1988. Biochem. J.252, 275.
Hisadome, T., et al. 1980. Gastroenterol. Jpn.15, 257.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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