345814-M

Gentamycin Sulfate

≥590 μg/mg, powder, NMD inhibitor, Calbiochem^®

• Synonym(s): Gentamycin Sulfate, NMD Inhibitor II
• CAS Number: 1405-41-0
• MDL number: MFCD00270181
• UNSPSC Code: 12352200
• NACRES: NA.22

Properties

• product name: Gentamycin Sulfate, Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations.
• Quality Level: 200
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• concentration: ≥590 μg/mg (anhydrous)
• color: white to off-white
• solubility: water: 10 mg/mL
• storage temp.: 2-8°C
• InChI: 1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1
• InChI key: RDEIXVOBVLKYNT-HDZPSJEVSA-N

Description

General description

Autoclavable. Stable over a wide pH range at 37°C for up to 15 days.

Broad-spectrum cell culture antibiotic that is non-toxic to viruses and mammalian cells at anti-bacterial and anti-mycoplasmal concentrations. Its extended stability and the slow development of bacterial resistance allow long-term virus and tissue culture studies. Composed of three closely related compounds: gentamycin C₁, C_1a, and C₂. Reduces sphingomyelinase activity in fibroblasts. Molecular weight of C₂ free base = 463.0.

Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Its extended stability and slow development of bacterial resistance allow long-term virus and tissue culture studies. Composed of three closely related components: gentamycin C₁, C_1a, and C₂. Reduces sphingomyelinase activity in fibroblasts. M.W. refers to C₂ free base form.

M.W. 463.0 (C₂, free base).

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C. Material is autoclavable. Stable over a wide pH range at 37°C for up to 15 days.

Other Notes

Montenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable