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Millipore

Centrifree® Ultrafiltration Centrifugal Filters

MWCO 30 kDa, sample volume 1 mL, Ultracel® PL regenerated cellulose membrane

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Synonym(s):
Centrifuge concentrator tube
eCl@ss:
36100101

material

EPDM rubber O-ring
EPDM rubber seal
Ultracel® PL regenerated cellulose membrane
polycarbonate base
polyethylene cup
styrene-acrylonitrile (SAN) reservoir (for sample)

Quality Level

sterility

non-sterile

manufacturer/tradename

Centrifree®

parameter

1 mL sample volume

L

95 mm

device volume

1 mL

diam.

1.6 cm

filtration area

0.92 cm2

pore size

30 kDa MWCO

shipped in

ambient

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This Item
MRCPRT010UFC710008UFC200324
sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

manufacturer/tradename

Centrifree®

manufacturer/tradename

Microcon®

manufacturer/tradename

Amicon® Ultra, Centricon®

manufacturer/tradename

Amicon® Ultra

pore size

30 kDa MWCO

pore size

10 kDa NMWCO

pore size

100 kDa MWCO

pore size

3 kDa NMWCO

parameter

1 mL sample volume

parameter

0.5 mL sample volume

parameter

15-70 mL sample volume

parameter

2 mL sample volume

L

95 mm

L

4.50 cm (1.8 in.)

L

121 mm

L

119.7 mm

General description

  • Separation of free from bound microsolute in serum, plasma, and other biological samples
  • Determine free therapeutic drugs, testosterone, thyroxin
  • Binding studies
  • New drug investigations
  • Deproteinization
  • For research and in vitro diagnostic use


The Centrifree® Ultrafiltration device with Ultracel regenerated cellulose membrane is ideal for separating free from bound microsolutes in serum, plasma, and other biological samples. The device is licensed for research use and in vitro diagnostic use. The device holds a sample volume of 1 mL with a hold-up volume of 10 µL.
PL
The Centrifree® Ultrafiltration device with Ultracel regenerated cellulose membrane is ideal for separating free from bound microsolutes in serum, plasma, and other biological samples. The device is licensed for research use and in vitro diagnostic use. The device holds a sample volume of 1 mL with a hold-up volume of 10 µL.

Features & Benefits:
•Separate unbound (free) therapeutic drugs, testosterone, thyroxin, etc.
•Enables accuracy in binding studies
•Critical for new drug investigations
•Facilitates deproteinization to reduce complexity or matrix interference of biological samples
•For research and in vitro diagnostic use

Applications:
Determination of Free Drugs, Testosterone, Thyroxin or Other Bioactives, Binding Studies, New Drug Investigations
Ultrafiltration

Features and Benefits

50 µL

Physical form

Clear

Legal Information

CENTRIFREE is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids


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Shivani Bhatt et al.
Nature communications, 11(1), 2360-2360 (2020-05-14)
Despite well-known peripheral immune activation in posttraumatic stress disorder (PTSD), there are no studies of brain immunologic regulation in individuals with PTSD. [11C]PBR28 Positron Emission Tomography brain imaging of the 18-kDa translocator protein (TSPO), a microglial biomarker, was conducted in
Shivani Bhatt et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 40(4), 695-704 (2019-03-22)
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes enzymatic conversion of cortisone into the stress hormone cortisol. This first-in-human brain imaging study characterizes the kinetic modeling and test-retest reproducibility of [18F]AS2471907, a novel PET radiotracer for 11β-HSD1. Eight individuals underwent one 180-min

Articles

This page discusses the principles and benefits of using ultrafiltration membranes in protein sample preparation. Possible applications include solvent exchange, protein sample concentration, or sample purification.

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