420290
IPTG, Hemidioxane Adduct
A free-flowing, hygroscopic carbohydrate that induces expression of the lac operon of E. coli by allosterically interacting with the repressor molecule.
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Synonym(s):
IPTG, Hemidioxane Adduct, Isopropyl-β-D-thiogalactopyranoside
Empirical Formula (Hill Notation):
C9H18O5S · 0.5C4H8O2
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
impurities
15.0% dioxane
color
white to off-white
solubility
water: 1%
ethanol: soluble
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C9H18O5S/c1-4(2)15-9-8(13)7(12)6(11)5(3-10)14-9/h4-13H,3H2,1-2H3/t5-,6+,7+,8-,9+/m1/s1
InChI key
BPHPUYQFMNQIOC-NXRLNHOXSA-N
General description
A free flowing carbohydrate that induces expression of the lac operon of E. coli by allosterically interacting with the repressor molecule. Inducer of β-D-galactosidase.
A free-flowing, hygroscopic carbohydrate that induces expression of the lac operon of E. coli by allosterically interacting with the repressor molecule. Inducer of β-D-galactosidase. This preparation contains 15% dioxane.
Warning
Toxicity: Carcinogenic / Teratogenic (D)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Mathur, A., et al. 2000. Cardiovasc. Res. 46, 126.
Chanda, B., and Mathew, M.K. 1999. Biochim Biophys. Acta 1416, 92.
Dedov, V.N., and Roufogalis, B.D. 1999. FEBS Lett. 456, 171.
Polla, B.S., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6458.
White, R.J., et al. 1996. J. Neurosci. 16, 5688.
Ankacrona, M., et al. 1995. Neuron 15, 961.
Reers, M., et al. 1995. Methods Enzymol. 260, 406.
Ravanello, M.P., and Kruby, D.E. 1994. J. Virol.68, 6401.
Schmitz, M.L., and Baeurerle, P.A. 1994. Biotechniques17, 714.
Cossarizza, A., et al. 1993. Biochem. Biophys. Res. Commun. 197, 40.
Lama, J., et al. 1992. Gene117, 185.
Zhang, Y., and Moss, B. 1991. Proc. Natl. Acad. Sci. USA88, 1511.
Rodriquez, J.F., and Smith, G.L. 1990. Nucleic Acids Res.18, 5347.
Date, T., et al. 1988. Biochem. Biophys. Res. Commun.151, 598.
Lee, S.G., et al. 1988. Biochemistry27, 2983.
Cho, S., et al. 1985. Biochem. Biophys. Res. Commun.128, 1268.
Chanda, B., and Mathew, M.K. 1999. Biochim Biophys. Acta 1416, 92.
Dedov, V.N., and Roufogalis, B.D. 1999. FEBS Lett. 456, 171.
Polla, B.S., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6458.
White, R.J., et al. 1996. J. Neurosci. 16, 5688.
Ankacrona, M., et al. 1995. Neuron 15, 961.
Reers, M., et al. 1995. Methods Enzymol. 260, 406.
Ravanello, M.P., and Kruby, D.E. 1994. J. Virol.68, 6401.
Schmitz, M.L., and Baeurerle, P.A. 1994. Biotechniques17, 714.
Cossarizza, A., et al. 1993. Biochem. Biophys. Res. Commun. 197, 40.
Lama, J., et al. 1992. Gene117, 185.
Zhang, Y., and Moss, B. 1991. Proc. Natl. Acad. Sci. USA88, 1511.
Rodriquez, J.F., and Smith, G.L. 1990. Nucleic Acids Res.18, 5347.
Date, T., et al. 1988. Biochem. Biophys. Res. Commun.151, 598.
Lee, S.G., et al. 1988. Biochemistry27, 2983.
Cho, S., et al. 1985. Biochem. Biophys. Res. Commun.128, 1268.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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