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434625

Sigma-Aldrich

Leukotriene B₄

≥97% (HPLC), oil, proinflammatory agent, Calbiochem®

Synonym(s):

Leukotriene B4, LTB₄, 5(S),12(R)-Dihydroxy-6- cis-8- trans-10- trans-14- cis-eicosatetraenoic Acid

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50 μL
$240.00

$240.00


Estimated to ship onJanuary 23, 2025


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50 μL
$240.00

About This Item

Empirical Formula (Hill Notation):
C20H32O4
CAS Number:
Molecular Weight:
336.47
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.77

$240.00


Estimated to ship onJanuary 23, 2025


Request a Bulk Order

Product Name

Leukotriene B4, Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium.

Quality Level

assay

≥97% (HPLC)

form

oil

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

clear

solubility

ethanol: soluble

shipped in

wet ice

storage temp.

−70°C

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dGTP =98%, solution, 100 mM, suitable for PCR, suitable for DNA sequencing

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dATP =98%, solution, 100 mM, suitable for DNA sequencing, suitable for DNA amplification

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manufacturer/tradename

Upstate®

manufacturer/tradename

Roche

manufacturer/tradename

-

manufacturer/tradename

Roche

form

liquid

form

solution

form

liquid

form

solution

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

technique(s)

affinity binding assay: suitable (G-protein)

technique(s)

DNA amplification: suitable, DNA sequencing: suitable, DNA synthesis: suitable, PCR: suitable

technique(s)

-

technique(s)

DNA amplification: suitable, DNA sequencing: suitable, DNA synthesis: suitable, PCR: suitable

General description

Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Polymorphonuclear leukocytes
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Flammable (J)

Physical form

In Ethanol.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2


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