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495414

Sigma-Aldrich

1-Oleoyl-2-acetyl-sn-glycerol

Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C.

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Synonym(s):
1-Oleoyl-2-acetyl-sn-glycerol, OAG, PKC Activator III
Empirical Formula (Hill Notation):
C23H42O5
CAS Number:
Molecular Weight:
398.58
MDL number:

Quality Level

assay

≥97% (HPLC)

form

oil

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

DMSO: soluble
ethanol: soluble

format

neat

shipped in

ambient

storage temp.

−20°C

InChI

1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1

InChI key

PWTCCMJTPHCGMS-YRBAHSOBSA-N

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This Item
317505310500110145
1-Oleoyl-2-acetyl-sn-glycerol Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C.

495414

1-Oleoyl-2-acetyl-sn-glycerol

1,2-Dioctanoyl-sn-glycerol Cell-permeable activator of protein kinase C (PKC).

317505

1,2-Dioctanoyl-sn-glycerol

D-erythro-Sphingosine, N-Acetyl- Biologically active, cell-permeable, non-physiological ceramide analog.

110145

D-erythro-Sphingosine, N-Acetyl-

form

oil

form

oil

form

oil (Clear), waxy solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

OK to freeze

General description

Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.
Note: 1 set = 10 x 500 µg.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Ca2+-dependent protein kinase C
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.

Other Notes

Florin-Christensen, J. 1993. Biochem. J.289, 783.
Benz, I., et al. 1992. J. Membr. Biol. 130, 183.
Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.
Gilmore, T., and Martin, G.S. 1983. Nature306, 487.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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