Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

8.07027

Sigma-Aldrich

1,2-Propylene oxide

for synthesis

Synonym(s):

1,2-Propylene oxide, 1,2-Epoxypropane, Methyloxirane

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C3H6O
CAS Number:
Molecular Weight:
58.08
MDL number:
UNSPSC Code:
12352005
EC Index Number:
200-879-2
NACRES:
NA.22

vapor pressure

585 hPa ( 20 °C)

Quality Level

assay

≥99.0% (GC)

form

liquid

autoignition temp.

430 °C

potency

380 mg/kg LD50, oral (Rat)
1245 mg/kg LD50, skin (Rabbit)

expl. lim.

1.9-36 % (v/v)

reaction suitability

reaction type: C-C Bond Formation

kinematic viscosity

0.37 cSt(20 °C)

mp

-112 °C

transition temp

flash point -38 °C

density

0.83 g/cm3 at 20 °C

InChI

1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3

InChI key

GOOHAUXETOMSMM-UHFFFAOYSA-N

Application


  • Enhanced poly(propylene carbonate) synthesis: Enhanced poly(propylene carbonate) materials were developed through a one-pot synthesis from carbon dioxide, propylene oxide, and a carboxylic dianhydride, showing significant improvements in yield strength when the feed molar ratio of dianhydride to propylene oxide was increased (X Chen et al., 2018).

  • Copolymerization with carbon dioxide: A study on the copolymerization and terpolymerization of carbon dioxide/propylene oxide/phthalic anhydride using a cobalt salen complex demonstrated efficient synthesis without forming ether linkages (JY Jeon et al., 2014).

  • Polymer architectures: Innovative polymer architectures were explored in the synthesis of poly(ethylene oxide), propylene oxide, and other alkylene oxides, which include novel bioconjugation techniques (J Herzberger et al., 2016).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.828 - 0.832
Identity (IR): passes test

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

-36.4 °F - Equilibrium method

flash_point_c

-38 °C - Equilibrium method


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service