8.07492

Pyrrole

for synthesis

• Synonym(s): Pyrrole
• Empirical Formula (Hill Notation): C₄H₅N
• CAS Number: 109-97-7
• Molecular Weight: 67.09
• MDL number: MFCD00005216
• UNSPSC Code: 12352005
• EC Index Number: 203-724-7
• NACRES: NA.22

Properties

• vapor pressure: 8.7 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥97.0% (GC)
• form: liquid
• autoignition temp.: 550 °C
• potency: 137 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 3.10-14.8 % (v/v)
• pH: >6 (20 °C, 10 g/L in H₂O)
• bp: 130-131 °C/1013 hPa
• mp: -24 °C
• transition temp: flash point 39 °C
• density: 0.97 g/cm³ at 20 °C
• storage temp.: 2-8°C
• InChI: 1S/C4H5N/c1-2-4-5-3-1/h1-5H
• InChI key: KAESVJOAVNADME-UHFFFAOYSA-N

Description

Application

• Therapeutic potential of pyrrole and pyrrolidine analogs: This review highlights the significant therapeutic potential of pyrrole derivatives, particularly in pharmacological contexts, underscoring their importance in drug development (Basha et al., 2022).
• Living on pyrrolic foundations–Advances in natural and artificial bioactive pyrrole derivatives: Discusses the role of pyrrole as a crucial building block in bioactive compounds, emphasizing its versatility and broad application range in medicine and synthetic chemistry (Domagala et al., 2015).
• Active methylenes in the synthesis of a pyrrole motif: Reviews recent advancements in synthesizing pyrrole motifs using active methylenes, crucial for developing pharmaceuticals and optoelectronic materials (Khajuria et al., 2016).
• Bioactive pyrrole-based compounds with target selectivity: Focuses on pyrrole-based compounds in drug discovery, highlighting their efficacy and target selectivity which are pivotal in the development of new therapeutics (Petri et al., 2020).
• Pyrrole as a promising electrolyte additive to trap polysulfides for lithium-sulfur batteries: Explores the use of pyrrole in enhancing the efficiency of lithium-sulfur batteries, demonstrating its utility beyond pharmaceutical applications (Yang et al., 2017).

Analysis Note

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.967 - 0.971
Identity (IR): passes test

Safety Information

• pictograms: GHS02,GHS05,GHS06
• signalword: Danger
• hcodes: H226 - H301 - H318 - H332
• pcodes: P210 - P233 - P280 - P301 + P310 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 96.8 °F - closed cup
• flash_point_c: 36 °C - closed cup