8.18718

Vanillin

for synthesis

• Synonym(s): Vanillin, 4-Hydroxy-3-methoxybenzaldehyde
• Linear Formula: (CH₃O)(OH)C₆H₃CHO
• CAS Number: 121-33-5
• Molecular Weight: 152.15
• MDL number: MFCD00006942
• UNSPSC Code: 12352114
• EC Index Number: 204-465-2
• NACRES: NA.22

Properties

• vapor pressure: 0.0029 hPa ( 25 °C)
• Quality Level: 200
• assay: ≥99.0% (HPLC)
• form: powder
• autoignition temp.: >400 °C
• potency: ≥4200 mg/kg LD₅₀, oral (Rat); >5010 mg/kg LD₅₀, skin (Rabbit)
• reaction suitability: reagent type: reductant
• pH: 4.3 (20 °C, 10 g/L in H₂O)
• mp: 80-83.5 °C
• transition temp: flash point 160 °C
• solubility: 9 g/L
• density: 1.06 g/cm³ at 20 °C
• bulk density: 600 kg/m³
• storage temp.: 2-30°C
• InChI: 1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
• InChI key: MWOOGOJBHIARFG-UHFFFAOYSA-N

Description

Application

• Vanillin formation from ferulic acid in Vanilla planifolia is catalysed by a single enzyme: This study identifies that a single hydratase/lyase is responsible for converting ferulic acid to vanillin in Vanilla planifolia, providing insights into the natural vanilla flavor production process (NJ Gallage et al., 2014).


• Overview of the role of vanillin in neurodegenerative diseases and neuropathophysiological conditions: This review covers the role of vanillin in various neurodegenerative conditions, focusing on its pharmacological properties and applications in this field (C Iannuzzi et al., 2023).

Analysis Note

Assay (HPLC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 81 °C
Melting range (upper value): ≤ 83 °C
Identity (IR): passes test

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 319.6 - 321.4 °F - closed cup
• flash_point_c: 159.8 - 160,8 °C - closed cup