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8.51022

Sigma-Aldrich

Dabcyl-OSu

Novabiochem®

Synonym(s):

Dabcyl-OSu, N-(4-[4Æ-(Dimethylamino)phenylazo]benzoyloxy)succinimide

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About This Item

Empirical Formula (Hill Notation):
C19H18N4O4
CAS Number:
Molecular Weight:
366.37
MDL number:
UNSPSC Code:
12352108
NACRES:
NA.22

Quality Level

product line

Novabiochem®

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reagent type: fluorescent-labelling reagent

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

15-25°C

InChI

1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3

InChI key

IBOVDNBDQHYNJI-UHFFFAOYSA-N

General description

Pre-activated derivative for the introduction of the Dabcyl group during SPPS. The Dabcyl group quenches the fluorescence of EDANS, Mca, TET, JOE, FAM fluorophores, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.

Associated Protocols and Technical Articles
Chromogenic Labeling of Synthetic Peptides

Linkage

Replaces: 01-63-0105

Analysis Note

Color (visual): red
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Articles

Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.

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