Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

8.52413

Sigma-Aldrich

Fmoc-Cys(methylcarboxamide)-OH

for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-Cys(methylcarboxamide)-OH, N-α-Fmoc-S-methylcarboxamide-L-cysteine

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352111
NACRES:
NA.22

product name

Fmoc-Cys(methylcarboxamide)-OH, Novabiochem®

Quality Level

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

thiol

storage temp.

15-25°C

General description

A novel derivative for the introduction of carboxamidomethyl (Cam) modified cysteine residues by direct Fmoc SPPS. Cys(Cam) containing peptides are required as standards for MS quantitation of proteins.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Cysteine-Containing Peptides

Application

Fmoc-Cys(methylcarboxamide)-OH has been used as a building block in the synthesis of peptide-acridine conjugates that target RNA.

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (HPLC): ≥ 98.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.1 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service