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Key Documents

CC1062

Sigma-Aldrich

TIMP-1, recombinant, active human

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77

biological source

human

Quality Level

form

liquid

potency

1.38 x 10E-9 M IC50 (versus 6.7 x 10E-9 M MMP-1)

manufacturer/tradename

Chemicon®

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... TIMP1(7076)

General description

Human TIMP-1, isolated from CHO cells transfected with human TIMP-1 cDNA. A single band at 29kDa is noted by SDS-PAGE.

Packaging

5 μg/vial

Linkage

Replaces: CC1063

Physical form

Purified protein in 10 mM Sodium Phosphate, pH 7.3, 0.15M NaCl.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: varies by lot

Citation

Nagai, Y, (1984) Jpn. Jp. Inflam. 4:123-130

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Manufactured by Daiichi Fine Chemical Co., Ltd

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Francis G Spinale et al.
Circulation. Heart failure, 2(4), 351-360 (2009-10-08)
The direct consequences of a persistently increased myocardial expression of the unique matrix metalloproteinase (MMP) membrane type-1 (MT1-MMP) on myocardial remodeling remained unexplored. Cardiac-restricted MT1-MMPexp was constructed in mice using the full-length human MT1-MMP gene ligated to the myosin heavy

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