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MAB821

Sigma-Aldrich

Anti-Herpes Simplex Virus I & II Antibody, clone 4F10.3

clone 4F10.3, Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

clone

4F10.3, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable

isotype

IgG2a

shipped in

wet ice

Specificity

Checked by immunoenzymatic method and shown to be highly reactive to HSV-I strains "Mac" and "F", moderately reactive to HSV-II strain "G" and weakly reactive to HSV-II strain "Ms". Possible application: direct detection of HSV I and HSV II virus.

Application

Detect Herpes Simplex Virus I & II using this Anti-Herpes Simplex Virus I & II Antibody, clone 4F10.3 validated for use in ELISA & IF.
ELISA Type I 1:6400 Type II 1:100

IFA infected fibroblasts 1:800

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Purified immunoglubulin. Liquid in 0.02M PB with 0.25M NaCl.pH=7.6, 0.1% Sodium Azide.

Storage and Stability

Maintain at 2-8°C.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J M McSharry et al.
Journal of clinical microbiology, 36(4), 958-964 (1998-05-23)
A flow cytometric assay has been developed for the measurement of susceptibilities to ganciclovir of laboratory strains and clinical isolates of human cytomegalovirus (HCMV). The assay uses fluorochrome-labeled monoclonal antibodies to HCMV immediate-early and late antigens to identify HCMV-infected cells
Jianyun Liu et al.
Immunology, 140(2), 191-201 (2013-05-29)
CD1d-restricted T (natural killer T; NKT) cells are important for controlling herpesvirus infections. Interestingly, herpes simplex virus (HSV) can down-regulate CD1d-mediated activation of NKT cells. We have previously shown that the Thr322 residue in the cytoplasmic tail of human CD1d

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