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MAB8258

Sigma-Aldrich

Anti-Influenza A Antibody, nucleoprotein, clone A3

clone A3, Chemicon®, from mouse

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

A3, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

isotype

IgG

shipped in

wet ice

Specificity

Specific for the influenza A nucleoprotein. Stronger reactivity is observed with N2/N3-type Flu A strains. No cross reactivity seen to Influenza B or other respiratory viruses.

Immunogen

Epitope: nucleoprotein
Influenza A

Application

Detect Influenza A using this Anti-Influenza A Antibody, nucleoprotein, clone A3 validated for use in IF.
Indirect Immunofluorescence

Optimal working dilutions must be determined by the end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified

Storage and Stability

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Influenza Control Slides, Catalogue Number 5010-5

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

wgk_germany

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hannes Bucher et al.
The Journal of pharmacology and experimental therapeutics, 357(3), 606-618 (2016-03-27)
Viral infections trigger exacerbations in chronic obstructive pulmonary disease (COPD), and tiotropium, a M3 receptor antagonist, reduces exacerbations in patients by unknown mechanisms. In this report, we investigated whether tiotropium has anti-inflammatory effects in mice exposed to cigarette smoke (CS)
Hongbin Wang et al.
Cell discovery, 4, 14-14 (2018-04-06)
Iron is an essential nutrient for cell survival and is crucial for DNA replication, mitochondrial function and erythropoiesis. However, the immunological role of iron in viral infections has not been well defined. Here we found the iron salt ferric ammonium
Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein.
Soumitra Roy,Gary P Kobinger,Jianping Lin,Joanita Figueredo,Roberto Calcedo,Darwyn Kobasa et al.
Vaccine null
Jin H Kim et al.
Scientific reports, 12(1), 3152-3152 (2022-02-26)
Despite the availability of vaccines and antiviral therapies, seasonal influenza infections cause 400,000 human deaths on average per year. Low vaccine coverage and the occurrence of drug-resistant viral strains highlight the need for new and improved countermeasures. While influenza A
Graham D Williams et al.
Nature communications, 9(1), 465-465 (2018-02-02)
Influenza A virus nucleoprotein (NP) association with viral RNA (vRNA) is essential for packaging, but the pattern of NP binding to vRNA is unclear. Here we applied photoactivatable ribonucleoside enhanced cross-linking and immunoprecipitation (PAR-CLIP) to assess the native-state of NP-vRNA

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