MilliporeSigma

MC0SP03FS1

Millipore

Millistak+® HC Pro Pod Depth Filter

C0SP, filtration area 0.33 m2, hydrophilic

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Synonym(s):
Millistak+ HC Pro Pod Depth Filter, C0SP media series, 0.33 m 2 surface area
eCl@ss:
32031690

material

acrylic
polypropylene
silica filter aid

Quality Level

description

Primary clarification directly out of the bioreactor

product line

EMPROVE® Filter

feature

hydrophilic

manufacturer/tradename

Millistak+®

parameter

30 psid max. differential pressure (2.1 bar) at 25 °C (Reverse)
30 psid max. differential pressure (2.1 bar) at 80 °C (Forward)
50 psid max. inlet pressure (3.5 bar) at 80 °C

H

12.5 in. (32 cm)
317 mm

L

24.2 in. (62 cm)

depth

3.2 in. (8.1 cm)

filtration area

0.33 m2

impurities

<0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction)

input

sample type liquid

conductivity

18.9-41.5 μS/cm at 25 °C (product water)

filter grade

C0SP

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This Item
MD0SP03FS1MC0SP07FS1MD0SP07FS1
filtration area

0.33 m2

filtration area

0.33 m2

filtration area

0.77 m2

filtration area

0.77 m2

feature

hydrophilic

feature

hydrophilic

feature

hydrophilic

feature

hydrophilic

product line

EMPROVE® Filter

product line

EMPROVE® Filter

product line

EMPROVE® Filter

product line

EMPROVE® Filter

description

Primary clarification directly out of the bioreactor

description

Primary clarification directly out of the bioreactor

description

Primary clarification directly out of the bioreactor

description

Primary clarification directly out of the bioreactor

manufacturer/tradename

Millistak+®

manufacturer/tradename

Millistak+®

manufacturer/tradename

Millistak+®

manufacturer/tradename

Millistak+®

General description

The Millistak+® HC Pro Pod Depth Filter (high capacity synthetic media) is a synthetic depth filter providing a cleaner and more consistent depth filtration media over current diatomaceous earth (DE) and cellulose (CE) based filter offerings. This unit, featured in a Process Scale Pod format with a C0SP media grade, supports primary and secondary clarification as well as downstream filtration applications.

Application

Primary clarification directly out of the bioreactor

Features and Benefits

Synthetic materials of construction

  • Reduce TOC extractables and pre-use flush volume requirements by 50%
  • No beta glucans to interfere with limulous amoebocyte lysate (LAL) testing for bacterial endotoxins
  • Lot to lot consistency for successful development and implementation of robust clarification processes


Depth filter media formulation & design
  • Provide as much as two times the filtration capacity with equivalent filter retention properties over commercial DE-based benchmarks
  • Improved HCP impurity clearance


Disposable Pod device
  • Flexible, modular format offers scalability from 5 to 12,000 liters or more
  • Robust device format; easy to use and set up

Specifications

Filter Grade: C0SP
Trace metals were measured post pure water flush of 50 L/m2 of surface area and 24-hour static soak in pure water. Values based on average of metals extractibles data from three separate uPod device lots. The analysis was made by ICP-MS. The devices were not autoclaved.

Preparation Note

Sterilization Method
Integrity is maintained after 1 autoclave cycle of 60 min @ 123 ºC. Filtration performance may be impacted post autoclave. Recommended for post use decontamination only.

Analysis Note

Product Water Conductivity at 25°C: after a pure water flush 50 L/m2 (5 liter per ft2) of media surface area (300 LMH, 10 min). At the end of the flush, a sample was pulled for conductivity measurement. Devices were not autoclaved.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany

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